Circadian photic regulation of melatonin receptor density in rat suprachiasmatic nuclei: Comparison with light induction of fos-related protein

Author(s):  
M. Masson-P�vet ◽  
L. Bianchi ◽  
P. P�vet
1994 ◽  
Vol 641 (1) ◽  
pp. 92-98 ◽  
Author(s):  
François Gauer ◽  
Mireille Masson-Pevet ◽  
Jörg Stehle ◽  
Paul Pevet

1997 ◽  
Vol 233 (1) ◽  
pp. 49-52 ◽  
Author(s):  
François Gauer ◽  
Carole Schuster ◽  
Paul Pévet ◽  
Mireille Masson-Pévet

1999 ◽  
Vol 276 (4) ◽  
pp. R1078-R1086 ◽  
Author(s):  
Gabriela Klante ◽  
Karin Secci ◽  
Mireille Masson-Pévet ◽  
Paul Pévet ◽  
Berthe Vivien-Roels ◽  
...  

We investigated the possibility that strain-dependent differences in the diurnal pattern of wheel running activity rhythms are also reflected in the melatonin profiles. The inbred rat strains ACI/Ztm, BH/Ztm, and LEW/Ztm. LEW were examined for diurnal [12:12-h light-dark (LD)] wheel running activity, urinary 6-sulphatoxymelatonin (aMT6s) excretion, melatonin concentrations of plasma and pineal glands, and melatonin receptor density in the suprachiasmatic nuclei (SCN). ACI rats displayed unimodal activity patterns with a high level of activity, whereas BH and LEW rats showed multimodal activity patterns with ultradian components and reduced activity levels. In contrast, the individual daily profiles of aMT6s excretion and mean melatonin synthesis followed a unimodal time pattern in all three strains, suggesting that different output pathways of the SCN are responsible for the temporal organization of locomotor activity and pineal melatonin synthesis. In addition, melatonin synthesis at night and SCN melatonin receptor density at day were significantly higher in BH and LEW rats than in ACI rats. These results support the hypothesis of a long-term stimulating effect of melatonin on its own receptor density in the SCN.


1990 ◽  
Vol 87 (15) ◽  
pp. 5959-5962 ◽  
Author(s):  
N. Aronin ◽  
S. M. Sagar ◽  
F. R. Sharp ◽  
W. J. Schwartz

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